Multiple Skin Colored Nodules on both Legs in Patient with Positive QuantiFERON®-TB Gold Test.
- Author:
Mi Soo CHOI
1
;
Seung Phil HONG
;
Byung Cheol PARK
;
Myung Hwa KIM
Author Information
- Publication Type:Case Report
- Keywords: Nodular tuberculid; QuantiFERON®-TB Gold test; Tuberculid
- MeSH: Adult; Biopsy; Dermis; Diagnosis; Female; Humans; Inflammation; Leg*; Skin Pigmentation*; Skin*; South Africa; Subcutaneous Fat; Thorax; Tuberculosis, Cutaneous; Vasculitis
- From:Annals of Dermatology 2017;29(1):95-99
- CountryRepublic of Korea
- Language:English
- Abstract: Nodular tuberculid (NT) was originally described by Jordaan et al. in 2000 in 4 patients from South Africa. It appeared as nodules on the legs; the pathologic changes were situated in the deep dermis and adjacent subcutaneous fat. A 34-year-old woman visited our hospital with subcutaneous skin-colored or slightly erythematous round to oval nodules. Skin biopsies revealed granulomatous inflammation at the dermo-subcutaneous junction with vasculitis. Chest X-ray, tuberculosus (TB)-polymerase chain reaction and TB culture of the skin specimen were normal. A QuantiFERON®-TB Gold test (QUIAGEN, Germany) was positive, which suggested a diagnosis of latent TB infection. The patient was treated with anti-TB medication and her condition has not recurred. Herein, we report a case of a patient with latent TB diagnosed by a positive QuantiFERON®-TB Gold test whose skin lesions had the clinical and histopathologic features of NT.
