A Case of Nongerminomatous Germ Cell Tumor with Fulminant Course Concomitant Leptomeningeal Metastasis.
10.14791/btrt.2016.4.1.21
- Author:
Youn Beom JEONG
1
;
Kyu Chang WANG
;
Ji Hoon PHI
;
Ji Yeoun LEE
;
Jung Eun CHEON
;
Hyoung Jin KANG
;
Il Han KIM
;
Seung Ki KIM
Author Information
1. Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, Korea. nsthomas@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Germ cell tumor;
Pinealoma;
Neoplasm metastasis;
Cerebellar neoplasm;
Cerebrospinal fluid;
Tumor markers
- MeSH:
Cerebellar Neoplasms;
Cerebrospinal Fluid;
Child;
Germ Cells*;
Humans;
Male;
Neoplasm Metastasis*;
Neoplasms, Germ Cell and Embryonal*;
Pineal Gland;
Pinealoma;
Radiotherapy;
Biomarkers, Tumor
- From:Brain Tumor Research and Treatment
2016;4(1):21-25
- CountryRepublic of Korea
- Language:English
-
Abstract:
We present the case of a 9-year-old boy with a non-germinomatous germ cell tumor (NGGCT) in the pineal gland that exhibited a fulminant course following chemo- and radiotherapy. After the detection of the tiny cerebellar enhancing nodule at the end of chemo- and radiotherapy, tumor seeding progressed rapidly into the entire cisternal space. We herein report a rare case of NGGCT with fulminant clinical course of concomitant cerebellar seeding, with review of literature.