Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells.
10.4174/jkss.2011.81.2.146
- Author:
Young Hoe HUR
1
;
Ho Hyun KIM
;
Jin Shick SEOUNG
;
Kyoung Won SEO
;
Jin Woong KIM
;
Yong Yeon JEONG
;
Jae Hyuk LEE
;
Yang Seok KOH
;
Jung Chul KIM
;
Hyun Jong KIM
;
Chol Kyoon CHO
Author Information
1. Division of Hepatico Biliary Pancreatic Surgery, Department of Surgery, Chonnam National University Medical School, Gwangju, Korea. chcho@jnu.ac.kr
- Publication Type:Case Report
- Keywords:
Osteoclast-like giant cells;
Undifferentiated carcinoma;
Pancreas
- MeSH:
Abdominal Pain;
Anorexia;
Carcinoma;
Female;
Giant Cells;
Humans;
Immunohistochemistry;
Magnetic Resonance Imaging;
Pancreas;
Pancreas, Exocrine;
Pancreatectomy;
Spleen;
Splenectomy
- From:Journal of the Korean Surgical Society
2011;81(2):146-150
- CountryRepublic of Korea
- Language:English
-
Abstract:
Undifferentiated carcinoma with osteoclast-like giant cells is a rare neoplasm of the exocrine pancreas. Some similar cases have been reported, but the histogenesis of these tumors varies and is controversial. We report here on a case of undifferentiated carcinoma of the pancreas with osteoclast-like giant cells. A 77-year old woman presented with abdominal pain and anorexia. Abdominal computed tomography and magnetic resonance imaging showed an approximately 10 x 5 cm highly attenuated mass arising from the tail of the pancreas and invading the spleen and adjacent bowel loop. The initial impression was a malignant endocrine tumor or solid-pseudopapillary tumor of the pancreas. The patient underwent a distal pancreatectomy with splenectomy and left hemicolectomy. The histopathology and immunohistochemistry helped make the diagnosis that of an undifferentiated carcinoma with osteoclast-like giant cells of the pancreas.
