Reliability of Breast Ultrasound BI-RADS Final Assessment in Mammographically Negative Patients with Nipple Discharge and Radiologic Predictors of Malignancy.
10.4048/jbc.2016.19.3.308
- Author:
Chae Jung PARK
1
;
Eun Kyung KIM
;
Hee Jung MOON
;
Jung Hyun YOON
;
Min Jung KIM
Author Information
1. Department of Radiology, Breast Cancer Clinic, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea. mines@yuhs.ac
- Publication Type:Original Article
- Keywords:
Breast neoplasms;
Galactorrhea;
Mammography;
Ultrasonography
- MeSH:
Biopsy;
Breast Neoplasms;
Breast*;
Carcinoma, Ductal;
Female;
Galactorrhea;
Humans;
Information Systems;
Mammography;
Nipples*;
Pregnancy;
Retrospective Studies;
Ultrasonography*
- From:Journal of Breast Cancer
2016;19(3):308-315
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The purpose of this study was to retrospectively investigate the reliability of breast ultrasound (US) Breast Imaging Reporting and Data System (BI-RADS) final assessment in mammographically negative patients with pathologic nipple discharge, and to determine the clinical and ultrasonographic variables associated with malignancy in this group of patients. METHODS: A total of 65 patients with 67 mammographically negative breast lesions that were pathologically confirmed through US-guided biopsy were included. RESULTS: Of the 53 BI-RADS category 4 and 5 lesions, eight (15.1%) were malignant (six ductal carcinomas in situ, one invasive ductal carcinoma, and one solid papillary carcinoma). There was no malignancy among the remaining 14 category 3 lesions. Malignant lesions more frequently displayed a round or irregular shape (75.0%, 6/8; p=0.030) and nonparallel orientation (33.3%, 4/12; p=0.029) compared to the benign lesions. The increase in the BI-RADS category corresponded with a rise in the malignancy rate (p=0.004). CONCLUSION: The BI-RADS lexicon and final assessment of breast US reliably detect and characterize malignancy in mammographically negative patients with pathologic nipple discharge.
