Pulmonary Leukocytoclastic Vasculitis as an Initial Presentation of Myelodysplastic Syndrome.
10.4046/trd.2016.79.4.302
- Author:
Seung Hyun LEE
1
;
Jae Hyung KIM
;
Sejin PARK
;
Chang Youn WON
;
Joo Hyun LEE
;
Seong Yoon YI
;
Hye Kyeong PARK
;
Sun Hee CHANG
;
Hoon JUNG
;
Sung Soon LEE
;
Hyeon Kyoung KOO
Author Information
1. Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. gusrud9@paik.ac.kr
- Publication Type:Case Report
- Keywords:
Myelodysplastic Syndromes;
Vasculitis, Leukocytoclastic, Cutaneous;
Paraneoplastic Syndromes;
Pneumonia
- MeSH:
Adult;
Anemia;
Biopsy;
Biopsy, Needle;
Bone Marrow;
Dyspnea;
Fever;
Humans;
Lung;
Myelodysplastic Syndromes*;
Paraneoplastic Syndromes;
Pneumonia;
Prognosis;
Radiography, Thoracic;
Recurrence;
Systemic Vasculitis;
Vasculitis*;
Vasculitis, Leukocytoclastic, Cutaneous
- From:Tuberculosis and Respiratory Diseases
2016;79(4):302-306
- CountryRepublic of Korea
- Language:English
-
Abstract:
Systemic vasculitis involving the lung is a rare manifestation of myelodysplastic syndrome (MDS), and secondary vasculitis is considered to have poor prognosis. A 44-year-old man presented with fever and dyspnea of 1 month duration. A chest radiograph revealed bilateral multiple wedge shaped consolidations. In addition, the results of a percutaneous needle biopsy for non-resolving pneumonia were compatible with pulmonary vasculitis. Bone marrow biopsy was performed due to the persistence of unexplained anemia and the patient was diagnosed with MDS. We reported a case of secondary vasculitis presenting as non-resolving pneumonia, later diagnosed as paraneoplastic syndrome of undiagnosed MDS. The cytopenia and vasculitis improved after a short course of glucocorticoid treatment, and there was no recurrence despite the progression of underlying MDS.
