Antibiotic Components from the Rhizomes of Curcuma zedoaria.
- Author:
Choon Sik JEONG
1
;
Sang Hee SHIM
Author Information
1. College of Pharmacy, Duksung Women's University, Seoul 132-714, Korea. sangheeshim@duksung.ac.kr
- Publication Type:Original Article
- Keywords:
Curcuma zedoaria;
Zingiberaceae;
Sesquiterpene Ketolactone;
Antibacterial activity
- MeSH:
Bacillus cereus;
Curcuma*;
Diffusion;
Listeria monocytogenes;
Rhizome*;
Staphylococcus;
Terpenes;
Zingiberaceae
- From:Natural Product Sciences
2015;21(3):147-149
- CountryRepublic of Korea
- Language:English
-
Abstract:
Two terpenoids, including one uniquely aromatized one (1), were isolated from CH2Cl2-soluble fraction of MeOH extracts of Curcuma zedoaria. They were identified to be a sesquiterpene ketolactone (1) and orobanone (2), respectively on the basis of their NMR data. The structure of compound 1 was confirmed by X-ray chrystallography and the reported NMR assignments for 1 were revised in this study. Antibiotic activities for compounds 1 and 2 were evaluated using disk diffusion assay. Compound 1 showed potent antibacterial activities against Listeria monocytogenes and Staphylococcus pseudointermedius while compound 2 was active against Bacillus cereus.
