A Case of NK/T-Cell Lymphoma Complicated by a Squamous Cell Carcinoma of Hard Palate during Combination Chemotherapy and Radiation Therapy.
- Author:
Hang Lak LEE
1
;
Myung Ju AHN
;
Jung Hye CHOI
;
Woon Hyun JUN
;
Young Yuel LEE
;
In Soon KIM
;
Il Young CHOI
;
Se Jin JANG
;
Yong Wook PARK
Author Information
1. Department of Internal Medicine Hanyang University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
NK/T-cell Lymphoma;
Second Primary Cancer;
Squamous Cell Carcinoma;
Hard Palate
- MeSH:
Carcinoma, Squamous Cell/*pathology/therapy;
Case Report;
Combined Modality Therapy;
Fatal Outcome;
Human;
Killer Cells, Natural;
Lymphoma, T-Cell/*pathology/therapy;
Male;
Middle Age;
Neoplasms, Second Primary/*pathology/therapy;
Oropharyngeal Neoplasms/*pathology/therapy;
Palatal Neoplasms/*pathology/therapy
- From:The Korean Journal of Internal Medicine
2002;17(1):69-72
- CountryRepublic of Korea
- Language:English
-
Abstract:
NK/T-cell lymphoma, which often shows an angiocentric growth pattern, is a distinct clinicopathologic entity highly associated with Epstein-Barr virus. The disease is characterized by a destruction of the upper respiratory tract, particularly the nasal cavity, palate and paranasal sinuses. Interestingly, NK/T-cell lymphoma is closely linked to a variety of complications, such as hemophagocytic syndrome, second primary cancer, sepsis and bleeding. Here we report a case of a 50-year-old man diagnosed initially as NK/T-cell lymphoma of the oropharynx and who developed a second primary carcinoma of the hard palate during combination chemotherapy and radiation therapy.
