Advances and current status of research on stroke and exosomes： A visual analysis
10.19845/j.cnki.zfysjjbzz.2025.0152
- VernacularTitle:脑卒中与外泌体研究进程及现状的可视化分析
- Author:
Qiaojun LI
1
;
Kaiqi SU
1
Author Information
1. Rehabilitation Center， The First Affiliated Hospital of Henan University of Traditional Chinese Medicine， Zhengzhou 450046， China
- Publication Type:Journal Article
- Keywords:
Stroke;
Exosomes;
Bibliometrics;
Visual analysis;
CiteSpace
- MeSH:
Stroke;
Exosomes;
Bibliometrics
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(9):810-822
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the research hotspots， development trends， and potential challenges in the field of stroke and exosomes based on bibliometric and visual analyses， and to provide scientific evidence for basic research and clinical translation. Methods The Web of Science database was used to obtain related articles published up to 2024， and CiteSpace and other tools were used to perform visual analyses from various aspects such as publication trends， collaboration networks， co-occurrence and clustering of keywords， and literature burst analysis. Results A total of 1 153 articles were included. The analysis showed an overall increasing trend in the number of publications per year. The institution with the highest number of publications was Henry Ford Health System， the author with the highest number of publications was Professor Chopp， and the journal with the highest number of articles Int J Mol Sci. High-frequency keywords included "extracellular vesicles" "ischemic stroke" and "stroke"， forming 12 research clusters， with neural repair and barrier protection as the key research directions. Conclusion The research on stroke and exosomes has been increasing year by year， with rapid development in recent years and the formation of an interdisciplinary pattern. Future studies should focus on the molecular mechanisms mediated by exosomes and their clinical application in stroke treatment， so as to promote the development of precision medicine and provide new therapeutic approaches.
