Quality control status and the prediction analysis of quality markers in Curculigo orchioides
- VernacularTitle:仙茅的质量控制现状及质量标志物预测分析
- Author:
Shicong WANG
1
;
Huayu WANG
1
;
Bo SHI
1
;
Mingsan MIAO
2
Author Information
1. School of Pharmacy，Henan University of Chinese Medicine，Zhengzhou 450046，China
2. School of Pharmacy，Henan University of Chinese Medicine，Zhengzhou 450046，China;Academy of Chinese Medicine/Henan Provincial Collaborative Innovation Center for R&D of the Whole Industry Chain of Henan Medicine，Henan University of Chinese Medicine，Zhengzhou 450046，China
- Publication Type:Journal Article
- Keywords:
Curculigo orchioides;
quality control;
quality markers;
prediction
- From:
China Pharmacy
2025;36(20):2604-2608
- CountryChina
- Language:Chinese
-
Abstract:
Curculigo orchioides refers to the dried rhizome of a plant from Amaryllidaceae family and exhibits a variety of pharmacological activities such as anti-osteoporosis， anti-inflammatory， anti-oxidation and immune regulation. However， the current quality control of C. orchioides mainly relies on the determination of a single indicator component （curculigoside）， which makes it difficult to reflect its quality fully. At the same time， factors such as processing methods， harvesting times， and place of origins can also lead to variations in the types and contents of chemical constituents in C. orchioides. Based on the theory of quality markers （Q-markers） for traditional Chinese medicine， a predictive analysis of the Q-markers of C. orchioides was conducted from seven perspectives： plant phylogeny and specificity of chemical constituents， traditional medicinal properties， efficacy， place of origin and harvesting period， processing methods， measurability of chemical constituents， and blood-entry constituents. It is preliminarily speculated that curculigoside， sakakin， orcinol gentiobioside， curculigoside B， curlignan， β-sitosterol， actinidioionoside， 2，6-dimethoxybenzoic acid， curculigoside C， glucosyringic acid， orcinol and stigmasterol are Q-markers of C. orchioides， providing a scientific basis for establishing a comprehensive and systematic quality evaluation system for C. orchioides.
