Academician WANG Yongyan′s experience in differentiating and treating motor neuron disease from the perspective of
10.3969/j.issn.1006-2157.2025.04.013
- VernacularTitle:王永炎院士从“虚气流滞、毒损络脉”辨治运动神经元病经验
- Author:
Liwei LIU
1
;
Yuxuan HUANG
2
;
Yipin FAN
2
Author Information
1. School of Basic Medicine, Chengdu University of Traditional Chinese Medicine;Academician WANG Yongyan s Academic and Ideological Research Office, Institute of Clinical Basic Medicine, Chinese Academy of Chinese Medical Sciences
2. School of Basic Medicine, Chengdu University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
motor neuron disease;
deficient-qi induced stagnation;
toxins damaging collaterals;
eliminate toxins and unblock collaterals;
flaccidity syndrome;
convulsive syndrome;
fei syndrome
- From:
Journal of Beijing University of Traditional Chinese Medicine
2025;48(4):552-558
- CountryChina
- Language:Chinese
-
Abstract:
This article summarizes Academician WANG Yongyan′s experience in the differentiation and treatment of motor neuron disease, which can be categorized into flaccidity syndrome, convulsive syndrome, and fei syndrome according to the clinical manifestations. These three syndromes may coexist, and the condition progressively worsens over time, which is believed to be caused by external pathogenic qi, based on "deficient-qi induced stagnation" , and with "toxins damaging collaterals" as the core etiology and pathogenesis. "Toxins damaging collaterals" involves three levels of qi collaterals, blood collaterals, and fluid collaterals, gradually overlapping and affecting the marrow collaterals. Academician WANG Yongyan′s theory is based on syndrome differentiation, breaking down the boundaries of flaccidity, convulsive, and fei syndromes according to different manifestations of the disease, and using the concept of "combined treatment" for treatment. The clinical presentation of motor neuron disease shows a bottom-up trend in the development of the sanjiao, and the combination of visceral syndrome differentiation and sanjiao syndrome differentiation can grasp the progress of the disease comprehensively. During the process of syndrome differentiation, the focus is on the use of xiang thinking, emphasizing the holistic correlation between diseases and syndromes and the integrated effect of reductionist analysis. Treatment is based on xiang differentiation and individualized treatment. The mid-stage of motor neuron disease is the key time point for the treatment of this disease. Based on the clinical symptoms of flaccidity, convulsive, and fei syndromes, where treatment should focus on reinforcing the spleen and kidney, combining moxibustion with herbal medicine. While targeting the disease, treatment should comprehensively apply the methods of "promoting, supplementing, softening, and warming" to eliminate toxins and unblock collaterals, and restore the neural regulation of the brain and spinal cord.
- Full text:2025102910292280625Academician WANG Yongyan′s experience in differentiating and treating motor neuron disease from the perspective of _deficient-qi induced stagnation and toxins damaging collaterals_.pdf
