Analysis of vaccination and infections of respiratory infectious diseases in children recovering from congenital heart disease in a specialized children's hospital in Shanghai after surgery
10.13200/j.cnki.cjb.004569
- VernacularTitle:上海市某儿童专科医院先天性心脏病康复儿童术后疫苗接种及呼吸道传染病感染状况分析
- Author:
DENG Pengfei
- Publication Type:Journal Article
- Keywords:
Congenital heart disease(CHD);
Children;
Respiratory infections;
Vaccines
- From:
Chinese Journal of Biologicals
2025;38(10):1203-1210
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the vaccination and respiratory infectious disease infections of children recovering from congenital heart disease(CHD) within one year after discharge from the hospital, and to provide a scientific basis for the development of respiratory infectious disease protection strategies for children recovering from CHD.Methods The children recovering from CHD after cardiac surgery at Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, from January to August 2023, were recruited as the subjects, and a follow-up survey on their parents or guardians was conducted one year after discharge to analyze the vaccination and respiratory infectious disease status of the enrolled children.Results A total of 200 children recovering from CHD were followed up, and the mean age was(31. 13 ± 19. 94)months. Among them, 94(47. 00%) were male and 106(53. 00%) were female. Regarding the protection pathways against respiratory infectious diseases, frequent opening of windows and ventilation at home(85. 50%), washing hands with hand sanitizer frequently(77. 00%), and wearing masks for babies in public places(41. 00%) were the main choices, and fewer chose to be able to vaccinate their babies in time when their condition stabilized(18. 00%) and to have other members of the family take the initiative to be vaccinated against influenza or pneumonia(6. 00%), and parents of different literacy levels wearing masks for their babies in public places(χ~2 = 10. 356, P = 0. 013) and being able to vaccinate their babies in time when their condition stabilized(χ~2 = 4. 370, P = 0. 041) exhibited statistically significant differences. Regarding respiratory infectious disease infections, children recovering from CHD mainly suffered from mycoplasma pneumonia(22. 50%) and influenza(12. 50%), with a smaller proportion suffering from whooping cough(1. 50%) and COVID-19(2. 50%), and there were two(66. 67%) hospitalizations for influenza in children at < 37 gestation weeks and two(9. 09%) at ≥ 37 gestation weeks with a statistically significant difference(χ~2 = 6. 512, P = 0. 011).Conclusion Parents of children recovering from CHD have a weak awareness of active vaccination and the construction of a family protection circle, and children recovering from CHD have a higher risk of mycoplasma pneumonia and influenza infections. Health education of parents of children recovering from CHD on vaccine-related knowledge should be strengthened to alleviate parental vaccine hesitancy and increase the coverage rate of respiratory infectious disease-related vaccination in this population.
