Influencing factors and occurrence status of metabolic syndrome in adult patients with hypopituitarism during hospitalization
10.3969/j.issn.1006-2483.2025.05.027
- VernacularTitle:成人腺垂体功能减退症患者住院期间代谢综合征发生现状及影响因素分析
- Author:
Lina JIANG
1
;
Jing XU
1
;
Chao SHI
1
;
Ruihua ZHANG
1
Author Information
1. Department of Endocrinology , the First Affiliated Hospital of Xinjiang Medical University , Urumqi , Xinjiang 830054 , China
- Publication Type:Journal Article
- Keywords:
Adult;
Hypopituitarism;
Metabolic syndrome
- From:
Journal of Public Health and Preventive Medicine
2025;36(5):121-124
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence status and influencing factors of metabolic syndrome (MS) in adult patients with hypopituitarism (HP) during hospitalization. Methods The data of adult HP patients who received treatment in the hospital were collected from March 2021 to March 2024. The prevalence status of MS in adult HP patients was counted, and logistic regression analysis was adopted to analyze the influencing factors of MS in adult HP patients. Results Among the 308 adult HP patients in this study, 121 cases developed MS and 187 cases did not develop MS, and they were included in the MS group (n=148) and the non-MS group (n=232). The incidence of MS in adult HP patients was 38.95% (148/380). Compared with the non-MS group, the levels of high-density lipoprotein cholesterol, serum total cholesterol and low-density lipoprotein cholesterol in the MS group were higher, the waist circumference was larger, and the growth hormone was lower (P<0.05). After logistic regression analysis, it was found that high-density lipoprotein cholesterol (OR=1.069, 95%CI: 1.010-1.132, P=0.021), total serum cholesterol (OR=1.065, 95%CI: 1.014-1.119, P=0.012), low-density lipoprotein cholesterol (OR=1.055, 95%CI: 1.005-1.108, P=0.031), waist circumference (OR=1.063, 95%CI: 1.006-1.123, P=0.030) and growth hormone (OR=1.077, 95%CI: 1.019-1.138, P=0.009) could independently affect the occurrence of MS in adult HP patients (P<0.05). Conclusion Adult HP patients during hospitalization are often complicated with MS. High-density lipoprotein cholesterol, serum total cholesterol, low-density lipoprotein cholesterol, waist circumference, and growth hormone are factors affecting the occurrence of MS in adult HP patients.
