Influencing factors and epidemic trends of lung cancer in a Hospital in Zigong Prefecture in 2019 - 2023
10.3969/j.issn.1006-2483.2025.05.026
- VernacularTitle:2019—2023年自贡某医院肺癌流行趋势及影响因素分析
- Author:
Xiaoyan YANG
1
;
Liyang WEI
1
;
Qingfeng ZHANG
1
Author Information
1. Department of Thoracic and Cardiovascular Surgery , Fourth People's Hospital of Zigong City , Zigong , Sichuan 643000 , China
- Publication Type:Journal Article
- Keywords:
Essential hypertension;
Angiotensinogen;
Gene polymorphisms;
Interactions
- From:
Journal of Public Health and Preventive Medicine
2025;36(5):116-120
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the trend of lung cancer prevalence and influencing factors in a Hospital of Zigong from 2019-2023. Methods Select 2 835 lung cancer patients in Zigong region admitted to the Zigong Fourth People's Hospital from January 2019 to December 2023, and analyze the changes in the clinical characteristics and age strata of patients in different time periods in this group. Three thousand non-cancer respiratory patients in the same time period were included to compare the differences in patient data and to analyze the influencing factors affecting the changes in the characteristics of lung cancer in this region. Results There was an upward trend in the number of patients with pneumonia included between 2019 and 2023, with the highest volume of patients included in 2021 (609 cases). Over the 5-year period, the percentage of patients aged 0-39 years did not change significantly and accounted for a relatively low percentage. The proportion of patients aged 40-49 years increased (APC=0.69%, t=2.990, P<0.05), and the proportion of patients over 60 years old decreased, but to a lesser extent (APC=-0.25%, t=2.210, P<0.05). There were no significant differences in male percentage, lesion site, distant metastasis, smoking history and tumor diameter among patients in different years (all P>0.05). There were significant differences in TNM stage and lymphatic metastasis among patients in different years (all P<0.05). Compared with 2019, the proportion of early stage and patients with lymph node metastasis showed an upward trend within five years (χ2early stage=9.153, Pearly stage=0.002; χ2lymph node metastasis=5.848, Plymph node metastasis=0.016). The factor associated with the change in age of lung cancer patients in different years was family history of lung cancer (P<0.01). Factors associated with histologic changes in lung cancer patients in different years were age, family history of lung cancer and smoking history (all P<0.05). Factors associated with changes in TNM distribution in lung cancer patients in different years were age, tumor diameter, family history of lung cancer and lymph node metastasis (all P<0.05). Factors associated with changes in lymph node metastasis in lung cancer patients in different years were tumor diameter and TNM stage (all P<0.05). Conclusion From 2019 to 2023, the age of patients with lung cancer in a Hospital in Zigong area showed a decreasing trend, which may be influenced by family history of lung cancer.Patients with TNM early stage and lymph node metastasis increased respectively, which influenced each other and were interfered by factors of age, tumor diameter, and family history of lung cancer.
