Epidemiological characteristics and related risk factors of respiratory virus infection of 502 children in 2022 - 2024
10.3969/j.issn.1006-2483.2025.05.024
- VernacularTitle:502例儿童呼吸道病毒感染流行病学特征及相关危险因素分析
- Author:
Yu ZHANG
1
;
Yijuan SUN
2
;
Feng ZHANG
3
;
Zhizhao ZHOU
1
Author Information
1. Department of Neonatology , Yangling Demonstration Zone Hospital , Xianyang , Shaanxi 712100 , China
2. Department of Pediatrics , Yangling Demonstration Zone Hospital , Xianyang , Shaanxi 712100 , China
3. Third Department of Pediatrics , Ankang Hospital of Traditional Chinese Medicine , Ankang , Shaanxi 725000 , China
- Publication Type:Journal Article
- Keywords:
Respiratory tract infection in children;
Virus;
Epidemiological characteristics
- From:
Journal of Public Health and Preventive Medicine
2025;36(5):106-110
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the epidemiological characteristics and risk factors of common viruses in children with respiratory tract infection in Yangling District, and to provide scientific basis for clinical formulation of effective prevention and control strategies. Methods The study subjects were 502 children with respiratory tract infection in Yangling Demonstration Zone Hospital from February 2022 to February 2024. 10 kinds of common respiratory infection viruses such as respiratory syncytial virus, parainfluenza virus, human rhinovirus, influenza B virus, influenza A virus, human adenovirus, enterovirus, coronavirus, human metapneumovirus and human Boca virus were detected by multiple real-time fluorescent polymerase chain reaction (PCR). According to the results of viral nucleic acid detection, 502 children were divided into positive detection group and negative detection group. Univariate and logistic multivariate regression analyses were adopted to analyze the risk factors of respiratory virus infection in children. Results Among the 502 children with respiratory tract infection, 112 cases were positive for viral nucleic acid detection, with a positive rate of 22.31%. Among the 95 cases were with single virus infection with a positive rate of 18.92%, mainly respiratory syncytial virus and parainfluenza virus, and 17 cases were with mixed virus infection, with the positive rate of 3.39%, mainly respiratory syncytial virus+parainfluenza virus mixed infection. After logistic multivariate analysis, it was found that age≤1 year old, onset in autumn and winter, monthly family income≤5000 yuan, concomitant congenital heart disease, maternal atopic disease history, maternal gestational diabetes mellitus, malnutrition and anemia were independent risk factors for respiratory virus infection in children (P<0.05). Conclusion Respiratory virus infection in acute hospitalized children in Yangling District is mainly a single virus, and is affected by many factors such as age of children, onset season, family monthly income and so on. Clinically, it is necessary to actively screen the above indicators of children and take active preventive measures to reduce viral infection.
