Relationship between Helicobacter pylori infection and disease severity and pathological type of inpatients with intestinal polyps
10.3969/j.issn.1006-2483.2025.05.019
- VernacularTitle:幽门螺杆菌感染与肠息肉住院患者病情严重程度及病理类型的关系
- Author:
Wei YOU
1
;
Dalin LU
1
;
Yan CHEN
1
;
Xin WANG
1
;
Yizheng FANG
1
;
Lunshan WANG
2
Author Information
1. Department of Gastroenterology ,Wuhu Fifth People's Hospital , Wuhu , Anhui 241000 , China
2. Department of Clinical Medical Laboratory , Wuhu Fifth People's Hospital ,Wuhu , Anhui 241000 , China
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Intestinal polyps;
Disease severity;
Pathological type;
Adenomatous polyps
- From:
Journal of Public Health and Preventive Medicine
2025;36(5):85-88
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between Helicobacter pylori (Hp) infection and disease severity and pathological type of intestinal polyps in inpatients. Methods The data of 303 inpatients with intestinal polyps in the hospital from August 2022 to February 2025 were collected and analyzed. The clinical characteristics of patients were analyzed, and the influencing factors of pathological types of polyps were explored. Results Among the 303 inpatients with intestinal polyps, there were 135 Hp positive cases and 168 Hp negative cases. The number of polyps, maximum polyp diameter, number of ileocecus/ascending colon/transverse colon polyps, number of descending colon/sigmoid colon/rectal polyps and adenomatous polyps in the Hp-positive group were higher than those in the Hp-negative group (P<0.05). Multivariate logistic regression analysis indicated that age [OR (95%CI)=1.03 (1.01-1.05)] and positive Hp[OR (95%CI)=2.61 (1.62-4.20)] were independent risk factors of occurrence of adenomatous polyps (P<0.05). ROC curve results revealed that the AUCs of age, positive HP and combination in the diagnosis of adenomatous polyps were 0.574, 0.608 and 0.646, and the 95%CI values were 0.509-0.638, 0.545-0.672 and 0.584-0.708 respectively. The efficiency of combination of the two indexes was higher than that of single diagnosis. Conclusion Hp infection is associated with disease severity in inpatients with intestinal polyps, and it may be involved in the occurrence and development of adenomatous polyps.
