Chikungunya fever: a comprehensive scientific understanding and prevention and control strategies
10.3969/j.issn.1006-2483.2025.05.001
- VernacularTitle:基孔肯雅热：全面科学认识与防控策略
- Author:
Xuesen XING
1
;
Yunfu WANG
2
Author Information
1. Hubei Provincial Disease Control and Prevention Administration , Wuhan , Hubei 430079 , China
2. Health Commission of Hubei Province ,Wuhan , Hubei 430079 , China
- Publication Type:Journal Article
- Keywords:
Chikungunya fever;
Aedes mosquitoes;
Clinical;
Control
- From:
Journal of Public Health and Preventive Medicine
2025;36(5):1-7
- CountryChina
- Language:Chinese
-
Abstract:
Chikungunya fever (CHIKF) has evolved from a regional, sporadically occurring infectious disease into a global public health challenge. The accelerated spread of the pandemic is primarily driven by the increasing adaptability and genetic variation of the virus , coupled with the expanding geographical range of Aedes albopictus mosquitoes . In endemic areas, asymptomatic carriers during the incubation period and subclinical infections constitute significant sources of transmission . Concurrently , pressure exists to prevent both imported cases and local transmission . While Aedes albopictus demonstrates higher transmission capability than Aedes aegypti , and transmission routes like blood transfusion and mother-to-child are uncommon in non-endemic areas , their associated risks remain relatively high in highly endemic regions. Most cases present with acute fever , arthralgia and rash , and As no specific antiviral treatment exists, clinical management primarily focuses on symptomatic and supportive care . The limitations of traditional chemical vector control and environmental management for mosquito elimination , combined with factors like insecticide resistance , result in suboptimal long-term vector control effectiveness . Furthermore , the limited accessibility of vaccines presents significant challenges to the sustainability of control strategies . Facing these multi-dimensional challenges , a comprehensive understanding of the disease and scientific control measures are imperative . This balances mosquito control with ecological protection through precise identification of breeding sites , optimization of vector control methods to minimize environmental impact , and enhanced efficiency in vector management . It requires integrating symptom control with causal intervention, developing more specific antiviral therapeutics and explore sequential therapeutic approaches (e.g. , “antiviral + immunomodulatory” regimens) to mitigate severe outcomes and chronic sequelae. It demands strengthening community-based governance integrated with precision-targeted interventions, establishing a robust end-to-end containment system (“imported cases–local transmission–source tracing–vector surveillance”) for rapid interruption of local transmission chains . Finally , it involves advancing the integration of biotechnology and intelligent monitoring to advance intelligent mosquito monitoring systems for real-time early warning , and construct a stable , sustainable vector control ecosystem integrating chemical , biological , and physical methods to suppress vector population density , reduce transmission risk, and elevate overall control efficacy.
