Advances in Bone Marrow Function Protection for Cervical Cancer Intensity-Modulated Radiotherapy Informed by Magnetic Resonance Imaging
10.3971/j.issn.1000-8578.2025.25.0182
- VernacularTitle:磁共振成像指导下宫颈癌调强放疗骨髓保护研究进展
- Author:
Guanghao JIN
1
;
Ke GU
1
Author Information
1. Department of Radiotherapy, Affiliated Hospital of Jiangnan University, Wuxi 214122, China;Wuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
- Publication Type:REVIEWS
- Keywords:
Cervical cancer;
Magnetic resonance imaging;
Intensity-modulated radiotherapy;
Bone marrow protection;
Dose distribution optimization
- From:
Cancer Research on Prevention and Treatment
2025;52(9):792-797
- CountryChina
- Language:Chinese
-
Abstract:
Cervical cancer is a common gynecological malignancy, and radiotherapy plays a crucial role in its treatment. However, conventional radiotherapy for cervical cancer often leads to bone marrow damage, considerably affecting patients’ quality of life and treatment outcomes. In recent years, the application of intensity-modulated radiotherapy (IMRT) and magnetic resonance imaging (MRI) technologies has provided novel solutions to this issue. IMRT optimizes dose distribution, minimizing radiation exposure to surrounding normal bone marrow tissues and thus considerably reducing damage. MRI allows for accurate tumor localization and monitoring, including organs at risk, such as the bone marrow, and providing precise guidance for radiotherapy. This article analyzes the feasibility and potential benefits of MRI-guided pelvic IMRT for bone marrow protection in cervical cancer, aiming to offer a basis for precise and effective bone marrow protection strategies in cervical cancer radiotherapy.
