Efficacy comparison of femtosecond laser-assisted in situ keratomileusis with small incision lenticule extraction in treating moderate myopia
10.3980/j.issn.1672-5123.2025.10.22
- VernacularTitle:FS-LASIK与SMILE治疗中度近视的疗效比较
- Author:
Dan ZHU
1
;
Dan ZHOU
1
;
Qingxia WANG
1
;
Xiaoyun MA
1
Author Information
1. Department of Ophthalmology, Affiliated Zhoupu Hospital of Shanghai University of Medicine and Health Sciences, Shanghai 201318, China
- Publication Type:Journal Article
- Keywords:
small incision lenticule extraction(SMILE);
femtosecond laser-assisted in situ keratomileusis(FS-LASIK);
moderate myopia;
efficacy
- From:
International Eye Science
2025;25(10):1672-1677
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To compare and analyze the efficacy of femtosecond laser-assisted in situ keratomileusis(FS-LASIK)with small incision lenticule extraction(SMILE)in the treatment of moderate myopia.METHODS:Retrospective study. A total of 100 patients(100 eyes)with moderate myopia admitted to our hospital from August 2022 to October 2024 were selected(all the data of the right eye were taken for study). The 52 cases in FS-LASIK group received FS-LASIK, while the 48 cases in SMILE group received SMILE. The patients were followed up for 6 mo, the visual recovery, spherical equivalent, corneal curvature, corneal Q value, central corneal thickness, corneal volume, high-order aberrations, corneal biomechanical parameters and incidence of complications were compared between the two groups.RESULTS: At 3 and 6 mo after surgery, the uncorrected visual acuity(UCVA)and spherical equivalent of both groups increased compared to before surgery(all P<0.05). At 6 mo after surgery, both groups showed a decrease in corneal curvature, central corneal thickness, and corneal volume, with the FS-LASIK group having a lower corneal volume; both groups showed a great increase in Q values, with the FS-LASIK group having a higher Q value(all P<0.001); the total high-order aberration, spherical aberration, and trefoil aberration all increased in both groups, with higher values observed in the FS-LASIK group(all P<0.001); the integrated radius(IR), inverse concave radius(ICR)and deformation amplitude ratio 2(DAR2)were all increased, while the stiffness parameter at first applanation(SP-A1), the highest concavity radius(HC-Radius)and the ambrosio's relational thickness to the horizontal profile(ARTh)were all decreased in both groups(all P<0.001). There was no statistical difference in the incidence of complications between two groups(P>0.05).CONCLUSION: Both FS-LASIK and SMILE can help improve the visual quality of patients with moderate myopia, and their early postoperative corneal morphological changes have their own characteristics. In addition, patients who receive FS-LASIK have larger corneal Q value and high-order aberrations after surgery.
