Isolated IgG4-related mediastinal disease: A case report
- VernacularTitle:孤立性IgG4相关性纵隔疾病一例
- Author:
Zhenhua JIAO
1
;
Jun YU
1
Author Information
1. Department of Thoracic Surgery, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, P. R. China
- Publication Type:Journal Article
- Keywords:
Immunoglobulin G4-related disease;
mediastinum;
isolated;
surgery;
case report
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2025;32(05):727-730
- CountryChina
- Language:Chinese
-
Abstract:
IgG4-related disease (IgG4-RD) is a chronic, immune-mediated inflammatory and fibrotic condition that can affect virtually any organ system. While some patients experience involvement of only a single organ, isolated IgG4-RD of the mediastinum is even rarer. This article reports a case of a 48-year-old male patient with isolated IgG4-RD of the middle mediastinum. After a biopsy failed to establish a definitive diagnosis, the patient underwent a right thoracotomy-assisted mediastinal tumor resection via video-assisted thoracoscopic surgery. The tumor was completely resected during the procedure, which lasted 130 minutes, with an estimated blood loss of approximately 50 mL. The patient had a favorable postoperative course and satisfactory clinical outcome. No glucocorticoid or other medical treatment was administered postoperatively, and there was no recurrence during a 6-month follow-up period.
