Pathogenic bacteria and risk factors of urinary tract infection in elderly patients with type 2 diabetes mellitus and construction of prediction model
10.3969/j.issn.1006-2483.2025.04.033
- VernacularTitle:老年2型糖尿病合并尿路感染患者病原菌危险因素及预测模型构建
- Author:
Jing TU
1
;
Yuanrui YANG
1
Author Information
1. Ward 2 , Cadre Department I , General Hospital of Western Theater Command , Chengdu , Sichuan 610016 , China
- Publication Type:Journal Article
- Keywords:
Elderly type 2 diabetes mellitus;
Urinary tract infection;
Pathogenic bacteria;
Prediction model
- From:
Journal of Public Health and Preventive Medicine
2025;36(4):145-148
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pathogenic bacteria and risk factors of urinary tract infection (UTI) in elderly patients with type 2 diabetic mellitus (T2DM), and construct a prediction model. Methods Elderly patients with T2DM who were admitted to General Hospital of Western Theater Command from January 2020 to March 2023 were selected. They were divided into the observation group (100 cases) and the control group (82 cases) according to the presence or absence of UTI. Pathogenic bacteria was detected, and influencing factors were analyzed. A prediction model was constructed, and its predictive value was evaluated. Results Escherichia coli was the main pathogenic bacteria of UTI in elderly patients with T2DM. There were significant differences between the two groups in terms of age, 24 h urinary albumin (UALB), serum creatinine (Scr) , blood urea nitrogen (BUN), fasting blood glucose (FBG), gender, complications, course of T2DM , length of hospital stay and serum albumin (ALB) (P<0.05). Logistic regression analysis found that advanced age, long course of T2DM, FBG ≥11.1mmol/L and high 24 hUA1b/Scr level were risk factors for UTI in elderly patients with T2DM, and high ALB level was a protective factor. The receiver operating characteristic (ROC) curve analysis showed that the area under the curve (AUC) of the constructed model to predict UTI in patients with T2DM was 0.978. The sensitivity and specificity were 91.00% and 97.56%. Conclusion Escherichia coli are main pathogenic bacteria of UTI in elderly patients with T2DM. UTI is related to factors such as patient age, course of T2DM and FBG. The prediction model constructed based on these factors is of high value in predicting UTI in elderly patients with T2DM. It is worthy of promotion in diagnosis and treatment.
