Association between obstructive sleep apnea hypopnea syndrome and cerebral white matter lesions
10.19845/j.cnki.zfysjjbzz.2025.0040
- VernacularTitle:阻塞性睡眠呼吸暂停低通气综合征与脑白质病变的相关性研究
- Author:
Yuan WANG
1
;
Yanmei ZHU
1
Author Information
1. The Second Affiliated Hospital of Harbin Medical University， Harbin 150000， China
- Publication Type:Journal Article
- Keywords:
White matter lesions;
Obstructive sleep apnea hypopnea syndrome;
Cerebral small vessel disease;
Lacunar infarct;
Cerebral microbleeds
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(3):204-208
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between obstructive sleep apnea hypopnea syndrome （OSAHS） and white matter lesions （WMLs）. Methods A total of 91 patients who attended Department of Neurology and Department of Epilepsy and Sleep Disorders in The Second Affiliated Hospital of Harbin Medical University from June 2019 to December 2020 and met the diagnostic criteria for WMLs were enrolled as WMLs group， and 61 patients without WMLs were enrolled as control group. All subjects underwent brain MRI and PSG examinations， and related data were collected， including demographic data， past history， personal history， laboratory examination， and imaging findings. Results The WMLs group had a prevalence rate of OSAHS of 92.3% and an AHI of （32.85±19.86） events/hour on PSG， which were significantly higher than those in the control group （P<0.05）. The Spearman rank correlation analysis showed a strong positive correlation between WMLs severity and OSAHS severity（r=0.602 52，P<0.0001）. Conclusion The WMLs group is more susceptible to OSAHS than the control group， and the severity of WMLs is positively correlated with the severity of OSAHS.
- Full text:2025071608591317025阻塞性睡眠呼吸暂停低通气综合征与脑白质病变的相关性研究.pdf
