Infiltrative basal cell carcinoma with nodal metastasis in a 74-year-old female: A case report

Author: Reynaldo Gabriel Paulino ¹ ; John Ricardo Chua ² ; Karen Damian ³ ; Erwin Gerard Geron ² ; Clarisse Veronica Mirhan ¹
Author Information

1. Department of Laboratories, Philippine General Hospital, University of the Philippines Manila, Manila, Metro Manila, NCR, Philippines
2. Department of Orthopaedics, Philippine General Hospital, University of the Philippines Manila, Manila, Metro Manila, NCR, Philippines
3. Department of Pathology, Philippine General Hospital, University of the Philippines Manila, Manila, Metro Manila, NCR, Philippines
Publication Type:Case Reports
Keywords: Squamous Cell Carcinoma In-situ; Infiltrative Basal Cell Carcinoma; Basaloid Cells
MeSH: Human; Female; Aged: 65-79 Yrs Old; Carcinoma, Basal Cell; X-ray
From: Philippine Journal of Pathology 2025;10(1):1-5
CountryPhilippines
Language:English
Abstract:
Basal cell carcinoma, the most common human malignancy, has a rare incidence of metastases ranging from 0.0028-0.55%. We report a case of a 74-year-old female with a 10-year history of an enlarging anterior thigh nodule. Wide resection and inguinal lymph node dissection revealed an infiltrative basal cell carcinoma with lymph node metastasis due to the presence of basaloid cells, limited peripheral palisading, loose stroma, extensive spread, perineural invasion and immunoreactivity to p40, BerEP4, and GATA3.
Full text:2025082913231302097pjp 10(1) CReport.pdf