The evolution of international definitions of fatty liver disease and insights into the working definition and features of the 2024 Chinese guideline
10.12025/j.issn.1008-6358.2025.20250107
- VernacularTitle:从国际脂肪性肝病定义的变迁看2024版中国指南的工作定义与特色
- Author:
Li CHEN
1
;
Jiangao FAN
2
Author Information
1. Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
2. Department of Gastroenterology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
- Publication Type:Monographicreport:Basicandclinicalresearchofmetabolicdysfunction-associatedfattyliverdisease
- Keywords:
metabolic dysfunction-associated fatty liver disease;
metabolic dysfunction-associated steatotic liver disease;
clinical practice guideline
- From:
Chinese Journal of Clinical Medicine
2025;32(3):321-326
- CountryChina
- Language:Chinese
-
Abstract:
Since 2020, the international community has successively proposed new nomenclatures for metabolic dysfunction-associated fatty liver disease (MAFLD) and metabolic dysfunction-associated steatotic liver disease (MASLD). In 2024, the Chinese Society of Hepatology updated and published the Guideline for the prevention and treatment of metabolic dysfunction-associated (non-alcoholic) fatty liver disease (version 2024). This review deeply analyzes the differences between MASLD and MAFLD in terms of concept, definition framework, and clinical management. On this basis, it provides an in-depth interpretation of the updated highlights and features of the working definition in the 2024 updated Chinese guideline.
