Review on toxic effects and mechanisms of rare earth neodymium

VernacularTitle:稀土钕的毒性效应及机制的研究进展
Author: Jing LENG ¹ ; Ning WANG ¹ ; Xinyu HONG ¹
Author Information

1. Institute of Chemical Toxicity Testing/ NHC Specialty Laboratory of Food, Safety Risk Assessment and Standard Development/State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.
Publication Type:Review
Keywords: rare earth element; neodymium; toxic effect; genotoxicity; reproductive toxicity; neurotoxicity
From: Journal of Environmental and Occupational Medicine 2025;42(6):770-773
CountryChina
Language:Chinese
Abstract: Neodymium, one of the important rare earth elements, is widely used in various fields such as industry, agriculture, and medicine. Neodymium and its compounds can accumulate in the human body through exposure to air, soil, food and so on, leading to various toxic effects. However, research on the toxicity effects and mechanisms of neodymium is still limited. This review summarized the toxic effects of neodymium on the liver, lung, and other organs, and discussed its genotoxicity, reproductive toxicity, neurotoxicity, and impacts on the endocrine system. The aim is to provide references for revealing the toxic effects of long-term low-dose exposure to neodymium in occupational exposure and environmental pollution scenarios.