Primary central nervous system lymphoma with positive anti-GFAP antibody in cerebrospinal fluid： a case report
10.19845/j.cnki.zfysjjbzz.2024.0023
- VernacularTitle:脑脊液抗GFAP抗体阳性的原发性中枢神经系统淋巴瘤1例报告
- Author:
Xiang YIN
1
;
Haitao REN
2
;
Li CUI
1
Author Information
1. Department of Neurology，The First Hospital of Jilin University，Changchun 130021，China
2. 北京协和医院神经内科，北京 100730
- Publication Type:Journal Article
- Keywords:
Primary central nervous system lymphoma;
Cerebrospinal fluid cytology;
Anti-GFAP antibody
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(2):119-122
- CountryChina
- Language:Chinese
-
Abstract:
This article reports a case of primary central nervous system lymphoma（PCNSL）. The patient was a young man with subacute onset，and the disease lasted for more than 8 months and had the main manifestations of gradually aggravated headache and dizziness. Cranial MRI showed ventricular dilatation，hydrocephalus，and meningeal enhancement. Dehydration treatment aiming to reduce intracranial pressure alleviated the symptom of headache in the early stage of the disease；the cerebrospinal fluid was tested positive for anti-GFAP antibodies，and the symptoms were improved temporarily after hormone treatment. However，the symptom of headache aggravated again after hormone reduction. Finally，the patient was diagnosed with PCNSL based on cerebrospinal fluid cytology and cerebrospinal fluid immunocytochemistry staining.
- Full text:2025070816123364512脑脊液抗GFAP抗体阳性的原发性中枢神经系统淋巴瘤1例报告.pdf
