Novel X-Clip transcatheter edge-to-edge repair system for treating severe functional mitral regurgitation: The first case report
- VernacularTitle:新型X-Clip经导管缘对缘修复系统应用于功能性重度二尖瓣反流患者首例报告
- Author:
Jiaqi DAI
1
;
Da ZHU
1
;
Shouzheng WANG
1
,
2
;
Xiangbin PAN
1
,
2
Author Information
1. Department of Structural Heart Center, Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated Cardiovascular Hospital of Kunming Medical University, Kunming, 650102, P. R. China
2. Department of Structural Heart Disease, National Center for Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100037, P. R. China
- Publication Type:Journal Article
- Keywords:
Mitral valve;
functional regurgitation;
transcatheter mitral valve edge-to-edge repair;
domestically developed devices;
case report
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2025;32(04):567-570
- CountryChina
- Language:Chinese
-
Abstract:
For patients with moderate-to-severe functional mitral regurgitation (FMR) who continue to experience heart failure symptoms despite optimized medical and device therapy, transcatheter mitral valve edge-to-edge repair (TEER) is increasingly becoming a reliable treatment option. With the continuous research and development and improvement of TEER-related devices, there are currently dozens of domestically developed TEER devices undergoing clinical trials in China. In this study, we report the first case of a patient with severe FMR treated with the X-Clip® TEER system. The patient, a 60-year-old male, suffered FMR attributed to dilated cardiomyopathy. Preoperative transthoracic echocardiography showed severe mitral regurgitation (4+). He underwent percutaneous repair using the X-Clip® system, and immediate postoperative ultrasound showed mild mitral regurgitation. At the 1-month follow-up, the patient’s symptoms and New York Heart Association (NYHA) functional class improved, and a follow-up transthoracic echocardiogram showed mild mitral regurgitation (1+).
