Prognostic Value in Preoperative Veterans RAND-12 Mental Component Score on Clinical Outcomes for Patients Undergoing Minimally Invasive Lateral Lumbar Interbody Fusion
	    		
		   		
		   			
		   		
	    	
    	- Author:
	        		
		        		
		        		
			        		Ishan KHOSLA
			        		
			        		
			        		
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			        		Fatima N. ANWAR
			        		
			        		;
		        		
		        		
		        		
			        		Andrea M. ROCA
			        		
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			        		Srinath S. MEDAKKAR
			        		
			        		;
		        		
		        		
		        		
			        		Alexandra C. LOYA
			        		
			        		;
		        		
		        		
		        		
			        		Keith R. MACGREGOR
			        		
			        		;
		        		
		        		
		        		
			        		Omolabake O. OYETAYO
			        		
			        		;
		        		
		        		
		        		
			        		Eileen ZHENG
			        		
			        		;
		        		
		        		
		        		
			        		Aayush KAUL
			        		
			        		;
		        		
		        		
		        		
			        		Jacob C. WOLF
			        		
			        		;
		        		
		        		
		        		
			        		Vincent P. FEDERICO
			        		
			        		;
		        		
		        		
		        		
			        		Gregory D. LOPEZ
			        		
			        		;
		        		
		        		
		        		
			        		Arash J. SAYARI
			        		
			        		;
		        		
		        		
		        		
			        		Kern SINGH
			        		
			        		
		        		
		        		
		        		
			        		
			        		Author Information
			        		
 - Publication Type:Original Article
 - From: Neurospine 2024;21(1):361-371
 - CountryRepublic of Korea
 - Language:English
 - 
		        	Abstract:
			       	
			       		
				        
				        	 Objective:To evaluate the effect of Veterans RAND 12-item health survey mental composite score (VR-12 MCS) on postoperative patient-reported outcome measures (PROMs) after undergoing lateral lumbar interbody fusion. 
				        	
Methods:Retrospective data from a single-surgeon database created 2 cohorts: patients with VR-12 MCS ≥ 50 or VR-12 MCS < 50. Preoperative, 6-week, and final follow-up (FF)- PROMs including VR-12 MCS/physical composite score (PCS), 12-item Short Form health survey (SF-12) MCS/PCS, Patient-Reported Outcomes Measurement Information System Physical Function (PROMIS-PF), Patient Health Questionnaire-9 (PHQ-9), visual analogue scale (VAS)-back/leg pain (VAS-BP/LP), and Oswestry Disability Index (ODI) were collected. ∆6-week and ∆FF-PROMs were calculated. Minimal clinically important difference (MCID) achievement rates were determined from established cutoffs from the literature. For intercohort comparison, chi-square analysis was used for categorical variables, and Student t-test for continuous variables.
Results:Seventy-nine patients were included; 25 were in VR-12 MCS < 50. Mean postoperative follow-up time was 17.12 ± 8.43 months. The VR-12 MCS < 50 cohort had worse VR-12 PCS, SF-12 MCS, PROMIS-PF, PHQ-9, VAS-BP, and ODI scores preoperatively (p ≤ 0.014, all), worse VR-12 MCS/PCS, SF-12 MCS, PROMIS-PF, PHQ-9, and ODI scores at 6-week postoperatively (p ≤ 0.039, all), and worse VR-12 MCS, SF-12 MCS, PROMIS-PF, PHQ-9, VAS-BP, VAS-LP, and ODI scores at FF (p ≤ 0.046, all). The VR-12 MCS < 50 cohort showed greater improvement in VR-12 MCS and SF-12 MCS scores at 6 weeks and FF (p ≤ 0.005, all). The VR-12 MCS < 50 cohort experienced greater MCID achievement for VR-12 MCS, SF-12 MCS, and PHQ-9 (p ≤ 0.006, all).
Conclusion:VR-12 MCS < 50 yielded worse mental health, physical function, pain and disability postoperatively, yet reported greater improvements in magnitude and MCID achievement for mental health. 
            