Relationship between Change in Physical Activity and Risk of Metabolic Syndrome: A Prospective Cohort Study
	    		
		   		
		   			
		   		
	    	
    	- Author:
	        		
		        		
		        		
			        		Doo Yong PARK
			        		
			        		
			        		
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			        		;
		        		
		        		
		        		
			        		On LEE
			        		
			        		;
		        		
		        		
		        		
			        		Yong Ho LEE
			        		
			        		;
		        		
		        		
		        		
			        		Chung Gun LEE
			        		
			        		;
		        		
		        		
		        		
			        		Yeon Soo KIM
			        		
			        		
		        		
		        		
		        		
			        		
			        		Author Information
			        		
 - Publication Type:Original Article
 - From: Journal of Obesity & Metabolic Syndrome 2024;33(2):121-132
 - CountryRepublic of Korea
 - Language:English
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		        	Abstract:
			       	
			       		
				        
				        	 Background:This study investigates the relationship between changes in physical activity levels and risk of metabolic syndrome. 
				        	
Methods:This study examined 1,686 adults aged 40 to 69 years from a community-based cohort study with complete 1st to 4th follow-up data between 2011 and 2020. Changes in physical activity were evaluated through baseline and follow-up surveys using physical activity questionnaires. Metabolic syndrome was diagnosed according to the International Diabetes Federation criteria. A survival analysis was conducted using a multivariate extended Cox regression model with a significance level set at P<0.05.
Results:Participants were divided into groups according to physical activity levels. The newly inactive group (vigorous physical activity ≤150 minutes at first follow-up) had a 36% increase in the hazard ratio (HR) for metabolic syndrome compared with the consistently inactive group (≤150 minutes at both baseline and first followup) (HR, 1.36; 95% confidence interval [CI], 1.04 to 1.79). The newly active group (walking ≤420 minutes per week at baseline and >420 minutes per week at first follow-up) had a 25% decrease in the HR for metabolic syndrome compared with the consistently inactive group (walking ≤420 minutes per week at both baseline and first follow-up) (HR, 0.75; 95% CI, 0.57 to 0.98).
Conclusion:Changes in physical activity levels are associated with risk of metabolic syndrome. These results provide important insights for future investigations into the link between physical activity changes and disease occurrence. 
            