Predictive factors for the diagnosis of autoimmune pancreatitis using endoscopic ultrasound-guided tissue acquisition: a retrospective study in Japan
- Author:
Keisuke YONAMINE
1
;
Shinsuke KOSHITA
;
Yoshihide KANNO
;
Takahisa OGAWA
;
Hiroaki KUSUNOSE
;
Toshitaka SAKAI
;
Kazuaki MIYAMOTO
;
Fumisato KOZAKAI
;
Haruka OKANO
;
Yuto MATSUOKA
;
Kento HOSOKAWA
;
Hidehito SUMIYA
;
Yutaka NODA
;
Kei ITO
Author Information
- Publication Type:Original Article
- From:Clinical Endoscopy 2025;58(3):457-464
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background/Aims:The factors affecting the detection rate of lymphoplasmacytic sclerosing pancreatitis (LPSP) using endoscopic ultrasound-guided tissue acquisition (EUS-TA) in patients with type 1 autoimmune pancreatitis (AIP) have not been thoroughly studied. Therefore, we conducted a retrospective study to identify the predictive factors for histologically detecting level 1 or 2 LPSP using EUS-TA.
Methods:Fifty patients with AIP were included in this study, and the primary outcome measures were the predictive factors for histologically detecting level 1 or 2 LPSP using EUS-TA.
Results:Multivariate analysis identified the use of fine needle biopsy (FNB) needles as a significant predictive factor for LPSP detection (odds ratio, 15.1; 95% confidence interval, 1.62–141; ¬¬p=0.017). The rate of good-quality specimens (specimen adequacy score ≥4) was significantly higher for the FNB needle group than for the fine needle aspiration (FNA) needle group (97% vs. 56%; p<0.01), and the FNB needle group required significantly fewer needle passes than the FNA needle group (median, 2 vs. 3; p<0.01).
Conclusions:The use of FNB needles was the most important factor for the histological confirmation of LPSP using EUS-TA in patients with type 1 AIP.
