Iris Metastasis of Non-small-cell Lung Cancer Inducing Anterior Uveitis and Secondary Glaucoma
10.3341/jkos.2024.65.12.810
- Author:
Ji Yeon MOON
1
;
Jung Hee IN
;
In Hwan CHO
Author Information
1. Department of Ophthalmology, Soonchunhyang University Cheonan Hospital, Soon Chun Hyang University College of Medicine, Cheonan, Korea
- Publication Type:Case Report
- From:Journal of the Korean Ophthalmological Society
2024;65(12):810-815
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Purpose:To report an iris metastasis of non-small-cell lung cancer inducing anterior uveitis and secondary glaucoma.Case summary: A 63-year-old woman presented to our hospital with vision impairment and pain in her right eye. She had been receiving systemic chemotherapy and radiation therapy to manage non-small-cell lung cancer for 2 years. Her best-corrected visual acuities were 25/40 oculus dexter (OD) and 20/25 oculus sinister; intraocular pressure was 52 mmHg OD. Slit-lamp examination revealed multiple round iris nodules and a 1+ inflammatory response in the anterior chamber of the right eye. Despite the maximimal tolerated medical therapy and laser trabeculotomy, the intraocular pressure was not controlled. Because iris metastasis of non-small-cell lung cancer was suspected, aqueous humor cytology and iris tissue biopsy were performed. Cytological analysis did not reveal malignant cells, but histopathological examination confirmed iris metastasis of non-small-cell lung cancer. A restaging procedure for lung cancer was performed, revealing new findings of lung and pelvic bone metastasis.
Conclusions:Through histopathological examination, it is possible to confirm iris metastasis of malignant tumors. Op
