Аnalgesic Activities Of Traditional Mongolian Drug Garidi-5

VernacularTitle:Уламжлалт Гарьд-5 Эмийн Өвдөлт Намдаах Нөлөөг Судалсан Дүн
Author: Uuganbayar B ¹ ; Ariunaa Z ¹ ; Oldokh S ¹ ; Chimedragchaa Ch ¹ ; Sugarjav E ¹ ; Molor-Erdene P ¹ ; Munkhzul G ¹
Author Information

1. School of Traditional medicine,MNUMS
Publication Type:Journal Article
Keywords: Garidi-5; antinociceptive effect; aspirin
From: Journal of Oriental Medicine 2013;4(1):64-70
CountryMongolia
Language:Mongolian
Abstract: Garidi-5, a traditional medicine composed of 5 herbs including Terminalia chebula Retz., Aconitum Kusnezoffii Reichb., Acorus calamus L., Saussurea lappa L., and musk ofMoschus moschiferus, has been used in traditional Mongolian medicine as an analgesic and antibacterial medicine. The aim of the study was to evaluate the central and peripheral analgesic action of traditional mongolian drug Garidi-5 in experimental animal models. Analgesic activity was assessed by tail flick method (for central action) and l acetic acid- induced writhing test (for peripheral action). Garidi-5 extract (20 mg/kg, 80, 200mg/kg p.o.) and aspirin (100 mg/kg) showed significant peripheral analgesic activity (p<0.05). Garidi-5 extract (20 mg/kg, 80, 200mg/kg p.o.) and Morphin (10 mg/kg, i.p.) also showed significant central analgesic activity (p<0.05). Conclusion: Biological activity substances were detected in the Traditional drug Garidi-5. Traditional drug Garidi-5 has analgesic effects.