Therapeutic Strategies for Drug-resistant Melanoma and Their Clinical Implications
- Author:
Ke HUANG
1
;
Myoung Ok KIM
Author Information
- Publication Type:Review
- From:Journal of Cancer Prevention 2025;30(1):7-11
- CountryRepublic of Korea
- Language:English
- Abstract: Melanoma is a malignant tumor originating from melanocytes, characterized by its high invasiveness and metastasis, leading to poor prognosis and high mortality. Early-stage melanoma is primarily treated with surgery; however, due to its metastatic nature, surgery becomes challenging in advanced stages. Treatment strategies for advanced or metastatic melanoma include chemotherapy, radiation therapy, and targeted therapy. However, melanoma’s propensity for rapid drug resistance remains a significant clinical challenge. This review summarizes the developments in the treatment of drug-resistant melanoma over the past decade and discusses the advantages and disadvantages of various therapeutic approaches and their clinical significance implications.
