Papillary Renal Cell Carcinoma in Transplanted Kidney and Xp11.2 Translocation/ Transcription Factor E3-Rearranged Renal Cell Carcinoma in the Native Kidney: A Case Report
- Author:
Min Hye KIM
1
;
Kyeong Ah KIM
;
Jeong Woo KIM
;
Seok Young LEE
;
Jae Woong CHOI
Author Information
- Publication Type:Case Report
- From: Journal of the Korean Society of Radiology 2024;85(2):437-444
- CountryRepublic of Korea
- Language:English
- Abstract: Concomitant renal cell carcinomas (RCC) of both native and allograft kidneys are extremely rare, and only a few cases have been reported in the available English literature. A particularly rare variant within the adult population is the Xp11.2 translocation/transcription factor E3 (TFE3)-rearranged RCC. Although few case reports of TFE3-rearranged RCC have been reported in children who underwent kidney transplantation (KT), no case of adults with TFE3-rearranged RCC following KT has been reported. Herein, we presented the radiological and pathological findings of a rare metachronous papillary RCC in the allograft kidney and TFE3-rearranged RCC in the native kidney. The TFE3-rearranged RCC in the native kidney exhibited slow expansion in size over five years. Radiologically, it appeared as a slightly enhanced, lobulated mass on contrast-enhanced CT. MRI revealed high signal intensity on T1-weighted images and low signal intensity on T2-weighted images.
