Association Between Body Mass Index and the Incidence of Laryngeal Cancer
10.3342/kjorl-hns.2023.00829
- Author:
Chan-Eui HONG
1
;
Young-Hoon JOO
;
Jin Kook KIM
;
Jae Hoon CHO
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Konkuk University, Seoul, Korea
- Publication Type:Original Article
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2024;67(8):447-451
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Background and Objectives:It is unknown whether the presence of low body mass index (BMI) influences the incidence of laryngeal cancer. In a national population-based study, we investigated their relationship retrospectively.Subjects and Method Using the data of Korean Health Insurance claims database, we selected adults aged 20 years or older who underwent a national health examination from January 1, 2007 to December 31, 2008 and were followed up until 2015 for the occurrence of laryngeal cancer. The hazard ratio of laryngeal cancer according to BMI and smoking status in the subjects was analyzed and adjusted for factors such as age, sex, alcohol consumption, and exercise status.
Results:Finally, a total of 13675470 subjects were included in the study, and we found that laryngeal cancer occurred in 3731 of those subjects. The risk of developing laryngeal cancer was significantly associated with underweight (BMI <18.5 kg/m2) even after adjustment (hazard ratio of 1.27; 95% confidence interval of 1.11-1.46). There was also a difference according to smoking status. Underweight was not associated with laryngeal cancer in never-smokers, but in ex-smokers and current smokers.
Conclusion:Being underweight can increase the risk of laryngeal cancer. In particular, this risk can increase if you drink and smoke at the same time.
