Green Synthesis of Silver Nanoparticles Using Jidanga and Banzdo Plant Extracts from Traditional Medicinal Sources
- VernacularTitle:Жиданга болон банздо ургамал ашиглан мөнгөний нанопартиклын фитосинтез явуулсан байдал
- Author:
Bayanmunkh A
1
;
Dejidmaa D
2
;
Oyuundelger G
3
;
Irekhbayr J
4
;
Odgerel O
5
;
Boldbaatar J
2
;
Batjargal B
3
Author Information
1. Laboratory of Food Analysis, Department of Biology, School of Arts and Sciences, National University of Mongolia;Drug Research Institute, Monos Group
2. Laboratory of Nanomaterials, Center of Nanoscience and Nanotechnology, Department of Chemical and Biological Engineering, School of Applied Science and Engineering, National University of Mongolia
3. Laboratory of Food Analysis, Department of Biology, School of Arts and Sciences, National University of Mongolia
4. Department of chemistry, School of Arts and Sciences, National University of Mongolia
5. Laboratory of Genetic Engineering, Department of chemical and biological engineering, School and applied science and engineering, National University of Mongolia
- Publication Type:Journal Article
- Keywords:
Jidanga;
Banzdo;
silver nanoparticles;
phytosynthesis
- From:Mongolian Medical Sciences
2023;205(4):47-58
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:The global urgency for environmentally friendly technologies has steadily intensified, and as a result,
the synthesis of silver nanoparticles with antibacterial properties derived from medicinal plants
traditionally used to combat bacterial infections has garnered significant interest.
Goals:This research endeavors to synthesize silver nanoparticles utilizing Jidanga and Banzdo plants,
widely recognized in traditional medicine, while elucidating their physical, chemical attributes, and
biological potential.
Methods:The physicochemical characteristics of these silver nanoparticles, synthesized through
phytosynthesis, were meticulously examined via various analytical techniques. Ultraviolet and visible
light spectrophotometry (UV/Vis), Photon Cross Correlation Spectroscopy (PCCS), Atomic Force
Microscope (AFM), Infrared Spectroscopy (FTIR), and X-ray Crystallography (XRD) were employed
for comprehensive analysis. Additionally, their antitumor efficacy was assessed via MTT assay utilizing
RAW264.7 cell cultures, while antibacterial properties were evaluated through agar diffusion tests
against selected bacterial strains.
Results:Silver nanoparticles exhibited distinctive UV/Vis absorption peaks at 407-426 nm, affirming their
composition. PCCS measurements revealed nanoparticles with hydrodynamic diameters spanning
from ~100 nm to ~450 nm, while AFM imaging showcased spherical nanoparticles ranging from ~35
nm to ~97 nm. Crystallography analysis identified both simple cubic and polycrystalline structures.
FTIR analysis unveiled the presence of organic compounds adsorbed onto the nanoparticle surfaces,
in addition to silver bonds. Notably, the aqueous and ethanolic extracts of Banzdo plants demonstrated
dose-dependent inhibition of RAW264.7 cell growth via the MTT assay. Furthermore, the silver
nanoparticles exhibited antibacterial activity against a range of test bacteria with inhibition zones
spanning 1-4 mm.
Conclusion:This study successfully synthesized silver nanoparticles utilizing Jidanga and Banzdo
plants from traditional medicine, comprehensively characterizing their physicochemical attributes
and demonstrating their biological activity. These findings hold promise for the future utilization of
phytosynthetically derived silver nanoparticles.
- Full text:2025060517454564985MMS-2023-205(4)-47-58.pdf
