Staged-Based Differentiation and Treatment of Pediatric Pertussis by Regulating Qi and Relieving Cough
10.13288/j.11-2166/r.2025.10.014
- VernacularTitle:调气止咳法分期辨治儿童百日咳
- Author:
Zhiyuan LU
1
;
Lili LIN
2
;
Qigang DAI
1
;
Shouchuan WANG
1
Author Information
1. Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing,210029
2. Institute of Pediatrics,Nanjing University of Chinese Medicine/Jiangsu Province University-level Key Laboratory of Children′s Health and Chinese Medicine
- Publication Type:Journal Article
- Keywords:
pertussis;
lung qi dysfunction;
regulating qi and relieving cough;
children
- From:
Journal of Traditional Chinese Medicine
2025;66(10):1060-1064
- CountryChina
- Language:Chinese
-
Abstract:
It is considered that the fundamental pathogenesis of pediatric pertussis lies in the dysfunction of lung qi, and it is advocated to treat the disease with the method of regulating qi and relieving cough. Clinically, the disease is divided into three stages for syndrome differentiation and treatment, initial coughing stage, spasmodic coughing stage, and prolonged coughing stage. In the initial coughing stage, the pathogenesis involves invasion by external pathogens and failure of lung qi to disperse; the treatment principle is to release the exterior, expel pathogens, ventilate the lungs, and relieve cough. For cold patterns, modified San'ao Decoction (三拗汤) is prescribed; for heat type, a self-formulated Qingqi Xuanfei Decoction (清气宣肺汤) is used. In the spasmodic coughing stage, the pathogenesis is the congealing of phlegm and fire with impaired lung purification; the treatment focuses on eliminating phlegm, dredging the meridians, purging the lungs, and relieving cough. Mild cases are treated with a self-formulated Tongluo Xiefei Decoction (通络泻肺汤), while severe cases are treated with a modified combination of Maxing Shigan Decoction (麻杏石甘汤) and Qianjin Weijing Decoction (千金苇茎汤). In the prolonged coughing stage, the pathogenesis involves the depletion of qi and yin and latent pathogens in a weakened lung; the treatment aims to tonify qi, nourish yin, moisten the lungs, and eliminate residual pathogens. For lung yin deficiency, modified Shashen Maidong Decoction (沙参麦冬汤) is used; for lung-spleen qi deficiency, a self-formulated Jianpi Gufei Decoction (健脾固肺汤) is prescribed.