Microscopic polyangiitis with severe anemia as the first clinical manifestation
10.5847/wjem.j.1920-8642.2025.052
- Author:
Jiali Wu
1
Author Information
1. Department of Emergency, Xiangya Hospital, Central South University, Changsha 410008, China
- Publication Type:Case Reports
- Keywords:
Microscopic polyangiitis;
anemia
- From:
World Journal of Emergency Medicine
2025;16(3):295-297
- CountryChina
- Language:English
-
Abstract:
Microscopic polyangiitis (MPA) is an autoimmune disorder characterized by pulmonary capillaritis and necrotizing glomerulonephritis triggered by the deposition of oligoimmune complexes. This condition primarily affects the lungs and kidneys.[1] The key pathological features in the lungs associated with MPA include pulmonary interstitial fibrosis and diffuse alveolar hemorrhage (DAH), which clinically present as cough, sputum production, hemoptysis, and dyspnea.[2] In this report, we present a patient with MPA complicated by severe anemia and DAH, notably without the typical symptoms of hemoptysis.
