Analysis of characteristics of adverse drug reactions in a hospital from 2021 to 2023
10.12206/j.issn.2097-2024.202404041
- VernacularTitle:2021−2023年某院药品不良反应的特点分析
- Author:
Yan WANG
1
;
Ming FANG
1
;
Hongwei SONG
1
;
Chao ZHONG
2
;
Feng XU
1
;
Ting ZHOU
1
Author Information
1. Sixth People’s Hospital South Campus, Shanghai Jiaotong University, Shanghai 201400, China.
2. Sixth People’s Hospital South Campus, Shanghai Jiaotong University, Shanghai 201400, China;School of Pharmacy, Shanghai University of Medical Science and Health, Shanghai 201318, China.
- Publication Type:Medicine&Clinical
- Keywords:
adverse drug reactions;
antibiotics;
rational drug use
- From:
Journal of Pharmaceutical Practice and Service
2025;43(4):200-204
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the characteristics of adverse drug reactions （ADR） reported in Sixth People’s Hospital South Campus, Shanghai Jiaotong University from 2021 to 2023, to provide reference for promoting rational clinical drug use. Methods ADR data reported in our hospital were collected retrospectively, including patients’ basic information, drugs causing adverse reactions, types of adverse reactions and outcomes. Descriptive analysis methods were used to summarize and analyze the data. Results A total of 979 cases of ADR were reported in our hospital from 2021 to 2023. The highest proportion of patients with ADR occurred in the age range of 31 to 50, and more male patients （63.5%）. The top five drugs involved with adverse reactions were antibiotics （48.8%）, Chinese medicine injections（19.2%）, vitamins（7.5%）, Chinese traditional medicine（7.2%）, equine tetanus immunoglobulin（6.3%）. Among antibiotics, cefuroxime, ceftazidime and cefotiam were the majority. The organs/systems involved in all ADR were mainly skin and accessories damage （55.4%）. The clinical manifestations were rash, itching, and maculopapular rash. Conclusion From 2021 to 2023, the most common drugs causing adverse drug reactions in our hospital were mainly antibacterial drugs, and the rational clinical use of antibacterial drugs still needs to be concerned.
