Full-process management of liver transplantation for hepatocellular carcinoma
10.12464/j.issn.1674-7445.2025083
- VernacularTitle:肝癌肝移植的全流程管理
- Author:
Guangdong WU
1
;
Qian LU
1
Author Information
1. Hepatobiliary Pancreatic Center, Beijing Tsinghua Changgung Hospital Affiliated to Tsinghua University, Key Laboratory of Digital Intelligence Hepatology of Ministry of Education, School of Clinical Medicine, Tsinghua University, Beijing 102218, China.
- Publication Type:Editorial
- Keywords:
Hepatocellular carcinoma;
Liver transplantation;
Milan criteria;
Downstaging therapy;
Bridging therapy;
Recurrence and metastasis;
Immunosuppressive agent;
Multi-disciplinary treatment
- From:
Organ Transplantation
2025;16(2):214-219
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma (HCC) is one of the most common cancers in clinical practice. Hepatectomy and liver transplantation are currently important treatment modalities for HCC. However, for patients with end-stage liver disease, liver transplantation is the optimal choice, as it can completely resect the tumor while restoring normal liver function. Nevertheless, clinical liver transplantation for HCC faces challenges such as a shortage of donor livers and a high risk of postoperative tumor recurrence and metastasis. How to select HCC patients for liver transplantation and effectively improve the prognosis of HCC liver transplantation has become a hot topic in clinical practice, involving multiple aspects from preoperative precise evaluation to long-term postoperative follow-up. Therefore, this article reviews the full-process management of HCC liver transplantation, including preoperative management, surgical management, postoperative management and the application of multidisciplinary comprehensive treatment in HCC liver transplantation, in order to provide references for improving the prognosis of HCC liver transplant recipients.
