Research on the regularity of traditional Chinese medicine in the treatment of perimenopausal syndrome based on data mining
10.3969/j.issn.1673-9701.2024.31.015
- VernacularTitle:基于数据挖掘探讨中医药治疗围绝经期综合征的用药规律
- Author:
Junlin LI
1
;
Hong MA
;
Min WEI
;
Ye LYU
;
Jun XIAO
Author Information
1. 江苏省中国科学院植物研究所药用植物研究中心,江苏南京 210014
- Keywords:
Perimenopausal syndrome;
Traditional Chinese medicine;
Data mining;
Medication regularity
- From:
China Modern Doctor
2024;62(31):64-67,84
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the regularity of traditional Chinese medicine in the treatment of perimenopausal syndrome(PMS).Methods The clinical research literatures on the treatment of PMS with traditional Chinese medicine published from January 2014 to January 2024 was retrieved from CNKI,Wanfang Data and VIP database,and the frequency,taste and meridian tropism of all drugs were analyzed.SPSS Modeler 18.0 software was used for data mining to determine the core drug combination and cluster analysis.Results A total of 142 literatures were included,including 142 prescriptions and 139 traditional Chinese medicines.The total frequency of medication was 1555 times,of which 26 drugs were used more than 20 times.The efficacy of drugs was mainly tonic drugs and heat-clearing drugs.The medicinal properties were mainly cold,and the taste was mostly sweet,which was mostly attributed to the liver,kidney and spleen meridians.Five commonly used drug pairs were obtained by association rule analysis.Three commonly used drug prescriptions were obtained by cluster analysis.Conclusion PMS is based on kidney deficiency,the pathogenesis of kidney yin deficiency,liver dysfunction,spleen and stomach dysplasia,the treatment of tonifying liver and kidney,nourishing yin and clearing heat,supplemented by harmonizing viscera.
