Study on the influencing factors of coronary CT angiography combined with CT-FFR on myocardial ischemia in coronary heart disease
10.3969/j.issn.1673-9701.2024.25.014
- VernacularTitle:冠状动脉CT血管成像联合CT-FFR对冠心病心肌缺血影响因素的研究
- Author:
Min XU
1
;
Hua QU
Author Information
1. 浙江中医药大学附属杭州市中医院放射科,浙江杭州 310007
- Keywords:
Coronary CT angiography;
Myocardial ischemia;
Plaque features;
Fractional flow reserve
- From:
China Modern Doctor
2024;62(25):66-69
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the imaging features of myocardial ischemia in patients with coronary heart disease by coronary CT angiography(CCTA)combined with coronary CT angiography derived fractional flow reserve(CT-FFR),and to find out the influencing factors of myocardial ischemia in patients with coronary heart disease.Methods A total of 86 patients who received CCTA examination in Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medicine University from January to November 2023 were retrospectively selected.According to the measured CT-FFR value,they were divided into ischemia group(CT-FFR≤0.80,45 cases)and non-ischemia group(CT-FFR＞0.80,41 cases).The plaque characteristics of two groups were compared,and the influencing factors of myocardial ischemia in patients with coronary heart disease were investigated by multivariate Logistic regression analysis.Results The proportion of diabetes mellitus in ischemia group was significantly higher than that in non-ischemia group(P＜0.05).A total of 150 coronary arteries showed plaque,with the majority located in the left anterior descending artery(114).A total of 212 plaques were analyzed,including 68 plaques in ischemic group and 144 plaques in non-ischemic group.The proportion of calcified plaque in non-ischemic group was significantly higher than that in ischemic group(P＜0.05).The degree of vascular stenosis,the volume of plaque,the proportion of lipid components and the volume of fibrous lipid components in ischemic group were significantly higher than those in non-ischemic group,and the volume of plaque fiber components was significantly lower than that in non-ischemic group(P＜0.05).Multivariate Logistic regression analysis showed that the degree of vascular stenosis(OR=1.054,P=0.026)and plaque volume(OR=1.027,P=0.048)were influencing factors of myocardial ischemia in patients with coronary heart disease.Conclusion The degree of vascular stenosis and volume of plaque are both factors affecting myocardial ischemia in patients with coronary heart disease,and targeted treatment can be carried out for these patients.
