Analyses on clinical characteristics and related factors of treatment outcomes in patients with nontuberculous mycobacterial pulmonary disease
10.3969/j.issn.1673-9701.2024.21.004
- VernacularTitle:非结核分枝杆菌肺病患者的临床特征及治疗转归相关因素分析
- Author:
Qiuju ZHOU
1
;
Xiaofen HUANG
;
Yingying CAI
Author Information
1. 浙江省台州医院检验科,浙江台州 318050
- Keywords:
Nontuberculous mycobacteria;
Nontuberculous mycobacterial pulmonary disease;
Mycobacterium avium complex pulmonary disease;
Treatment outcomes;
Adverse reaction
- From:
China Modern Doctor
2024;62(21):16-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective By analyzing the clinical characteristics and related factors of treatment outcomes in patients with nontuberculous mycobacterial pulmonary disease(NTM-PD)in Taizhou,this study provided reference for the management,diagnosis and treatment of NTM-PD.Methods Clinical characteristics of 167 patients with NTM-PD isolated in Taizhou Hospital of Zhejiang Province from January 2016 to December 2021 were retrospectively analyzed.The differences in clinical characteristics were compared between cured group and failed group of 83 cases with Mycobacterium avium complex pulmonary disease(MAC-PD).Results MAC-PD was the most common species among the 167 cases of NTM-PD,accounting for 94.6％,88 patients were treated.The cure rate was 47.7％.Compared with cured group,the patients in failed group had statistical differences in body mass index(BMI)≤ 18.5kg/m2,acid-fast bacilli smear-positive,combined with previous pulmonary tuberculosis,imaging with fibrous-cavernous type and unstandardized medication(P＜0.05).Conclusion MAC-PD is the most common among NTM-PD patients in Taizhou.BMI ≤ 18.5kg/m2,acid-fast bacilli smear-positive,combined with previous pulmonary tuberculosis,imaging with fibrous-cavernous type and unstandardized medication of MAC-PD were more difficult to treat.
