Progress of small intestinal neuroendocrine tumors
10.3760/cma.j.cn115355-20231208-00776
- VernacularTitle:小肠神经内分泌肿瘤的研究进展
- Author:
Lin CHEN
1
;
Min YANG
;
Jiansheng GUO
Author Information
1. 山西医科大学第一临床医学院，太原 030001
- Keywords:
Neuroendocrine tumors;
Intestine, small;
Diagnosis;
Treatment
- From:
Cancer Research and Clinic
2024;36(7):553-557
- CountryChina
- Language:Chinese
-
Abstract:
Small intestinal neuroendocrine tumor is a kind of tumor arising from neuroendocrine cells and with neuroendocrine function. Because of non-specific clinical manifestations, these patients are often diagnosed at advanced stage and the treatment method is lacking. In 2019, World Health Organization updated the classification of neuroendocrine tumor. In recent years, liquid biopsy, pancreastatin, somatostatin receptor function imaging provide a new possibility for early diagnosis and monitoring prognosis. The mammalian target of rapamycin inhibitor everolimus, the tryptophan hydroxylase inhibitor telotristat ethyl and the tyrosine kinase inhibitor surufatinib bring a new breakthrough to improve the clinical symptoms and prolong the survival time of small intestinal neuroendocrine tumor. This paper reviews the current situation and the latest research progress of small intestinal neuroendocrine tumor.
