Research progress of optical coherence tomography biomarkers in macular edema secondary to retinal vein occlusion
10.3760/cma.j.cn511434-20240311-00098
- VernacularTitle:视网膜静脉阻塞继发黄斑水肿的光相干断层生物学标志物的研究进展
- Author:
Junru LIU
1
;
Weili DONG
Author Information
1. 承德医学院附属医院眼科，承德 067000
- Keywords:
Retinal vein occlusion;
Macular edema;
Tomography, optical coherence;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2024;40(5):397-401
- CountryChina
- Language:Chinese
-
Abstract:
Retinal vein occlusion (RVO) is one of the most common retinal vascular diseases causing blindness, macular edema (ME) is often secondary to it, which causes serious visual impairment to patients. Imaging biomarkers in the changes of retina and choroid of ME secondary to RVO (RVO-ME) have important clinical value in the evaluation of condition, curative effect and visual acuity prediction of patients with RVO-ME. Among them, the disorganization of the retinal inner layers, the integrity of external limiting membrane and ellipsoid zone, and the change of central macular thickness are reliable indexes to evaluate the prognosis of visual acuity; hyperreflective foci, subretinal fluid and intraretinal fluid can be used as important parameters to reflect the level of inflammation; prominent middle limiting membrane and paracentral acute middle maculopathy are the objective basis for judging the degree of retinal ischemia; the changes of choroidal vascular index and choroidal thickness also have potential advantages in evaluating the progress of the disease. Accurately grasp the characteristics of biological markers of RVO-ME related optical coherence tomography is conducive to its reasonable and accurate use in the clinical diagnosis and treatment of RVO-ME, and helpful to further explore the pathogenesis of the disease.
