Clinical application of fluorescence laparoscopy in living donor left lateral sectionectomy for pediatric liver transplantation
10.3760/cma.j.cn421203-20231001-00114
- VernacularTitle:荧光腹腔镜在儿童活体肝移植左外叶供肝切取术中的应用
- Author:
Yi LUO
1
;
Jianjun ZHU
;
Yuting JIN
;
Dongwei XU
;
Qiang XIA
Author Information
1. 上海交通大学医学院附属仁济医院肝脏外科，上海 200127
- Keywords:
Child;
Liver transplantation;
Living donor liver transplantation;
Fluorescence;
Laparoscopic hepatectomy
- From:
Chinese Journal of Organ Transplantation
2024;45(5):323-328
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical efficacy of fluorescent laparoscopy versus conventional laparoscopy for living-donor hepatectomy and explore the application value of fluorescent cholangiography in pediatric living donor liver transplantation (LT) using left lateral lobe.Methods:From October 2016 to August 2023, retrospective analysis was conducted for the relevant clinical data from 302 recipients of laparoscopic left lateral lobe donor hepatectomy. There were 90 cases in conventional laparoscopy group and 212 cases in fluorescent laparoscopy group. After propensity score matching (PSM), 88 patients were enrolled into each group. The perioperative data such as operative duration, donor liver thermal ischemic time, number of graft bile duct openings, liver function parameters and complication rates at Day 1/3 postoperation of donors and recipients were compared between two groups. SPSS 27.0 statistical software was utilized for analysis. Independent sample t, Mann-Whitney U and chisquare tests were utilized for examining the inter-group differences. Results:In fluorescent laparoscopy group, the proportion of grafts with a single open left hepatic duct was 84.1 %(74/88) versus 70.5% (62/88) in conventional laparoscopy group with statistically significant difference ( P=0.031). No statistically significant inter-group differences existed in postoperative liver function recovery or short-term postoperative complications ( P>0.05 ). No statistically significant inter-group differences existed in short-term postoperative liver function recovery or hospitalization length ( P> 0.05). In terms of biliary complications, fluorescent laparoscopy group had no biliary complications while the incidence of biliary complications was 3.4% (3/88) in conventional laparoscopy group. However, inter-group difference was statistically insignificant ( P>0.05 ) . Conclusions:Living-donor LT using left lateral lobe under fluorescent laparoscopy may enhance the surgical safety for both donors and recipients.
