Liver transplantation for hepatocellular carcinoma, advancing in scientific exploration
10.3760/cma.j.cn113855-20240125-00069
- VernacularTitle:在科学探索中前进的肝癌肝移植
- Author:
Hao CHEN
1
;
Zhao LI
;
Jiye ZHU
;
Xiao XU
Author Information
1. 浙江大学医学院，杭州 310058
- Keywords:
Carcinoma, hepatocellular;
Liver transplantation;
Recurrence
- From:
Chinese Journal of General Surgery
2024;39(5):329-332
- CountryChina
- Language:Chinese
-
Abstract:
The result of liver transplantation (LT) for the treatment of hepatocellular carcinoma (HCC) is constrained by the high rates of tumor recurrence and metastasis. To remove this bottleneck, precise patient selection is crucial for individuals with HCC, and the goal of down-staging therapy is to transform patients exceeding transplantation criteria into suitable candidates. The difficulty in treating tumor recurrence and metastasis post-transplantation calls for more breakthroughs. Immunotherapy, as an emerging treatment modality, requires further exploration to enhance its safety and efficacy. The immunosuppression strategy is also a key factor in reducing tumor recurrence, requiring precise assessment and balanced control.
