Dermoscopic and reflectance confocal microscopic characteristics of five cases of erythema dyschromicum perstans
- VernacularTitle:持久性色素异常性红斑5例皮肤镜和反射式共聚焦显微镜特征分析
- Author:
You HUA
1
;
Haiyan REN
;
Xiuzu SONG
Author Information
- Keywords: Pigmentation disorders; Dermoscopy; Microscopy, confocal; Erythema dyschromicum perstans; Ashy dermatosis
- From: Chinese Journal of Dermatology 2024;57(9):830-832
- CountryChina
- Language:Chinese
- Abstract: Objective:To analyze the dermoscopic and reflectance confocal microscopic characteristics of erythema dyschromicum perstans (EDP), and to explore the value of dermoscopy and reflectance confocal microscopy (RCM) in the auxiliary diagnosis of EDP.Methods:Clinical data were retrospectively collected from 5 patients with EDP, who visited and were treated in the Department of Dermatology, Hangzhou Third People's Hospital from January to December 2020. Three typical lesions were chosen from each patient, and the 15 lesions were examined by dermoscopy and RCM. Skin specimens were taken from 2 cases at the observation sites for histopathological examination.Results:Among the 5 EDP patients, there were 3 males and 2 females, with an average age of 40.8 years (range, 24 - 62 years) and an average disease course of 15.7 months (range, 3 - 48 months). Disseminated Greyish-green patches on the trunk were observed in 3 cases, 1 case presented with lesions located on the bilateral upper limbs, and 1 presented with a solitary lesion on the neck. Dermoscopy showed that all 15 lesions exhibited a black pepper-like structure. RCM revealed focal liquefaction degeneration of basal cells in all 15 lesions. Histopathological examination of 2 cases showed focal liquefaction degeneration of basal cells and scattered pigmentophages in the dermal papilla.Conclusion:EDP has typical dermoscopic and RCM characteristics, which could provide a basis for its diagnosis and differential diagnosis.
