Clinical effects of Bushen Quyu Decoction combined with conventional treatment on patients with postmenopausal osteoporosis due to Kidney Deficiency and Blood Stasis
10.3969/j.issn.1001-1528.2024.08.017
- VernacularTitle:补肾祛瘀汤联合常规治疗对肾虚血瘀型绝经后骨质疏松症患者的临床疗效
- Author:
Li XIAO
1
;
Ju-Ying XIE
;
Yun LIU
;
Li-Ping HU
;
Xia CAO
;
Jun-Lin SHI
Author Information
1. 湘南学院医学影像检验与康复学院,湖南郴州 423000;湘南学院附属医院康复医学科,湖南郴州 423000
- Keywords:
Bushen Quyu Decoction;
conventional treatment;
postmenopausal osteoporosis;
Kidney Deficiency and Blood Stasis
- From:
Chinese Traditional Patent Medicine
2024;46(8):2601-2605
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the clinical effects of Bushen Quyu Decoction combined with conventional treatment on patients with postmenopausal osteoporosis due to Kidney Deficiency and Blood Stasis.METHODS One hundred and six patients were randomly assigned into control group(53 cases)for 6-month intervention of conventional treatment,and observation group(53 cases)for 6-month intervention of both Bushen Quyu Decoction and conventional treatment.The changes in clinical effects,TCM syndrome scores,bone metabolism indices(β-CTX,PINP,BGP),bone mineral density,oxidative stress indices(SOD,AOPP,MAOA)and incidence of adverse reactions were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P＜0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,β-CTX,BGP,AOPP,MAOA(P＜0.05),and increased PINP,bone mineral density,SOD(P＜0.05),especially for the observation group(P＜0.05).No significant difference in incidence of adverse reactions was found between the two groups(P＞0.05).CONCLUSION For the patients with postmenopausal osteoporosis due to Kidney Deficiency and Blood Stasis,Bushen Quyu Decoction combined with conventional treatment can safely and effectively improve bone mineral density,bone metabolism indices,and alleviate oxidative stress responses.
