Status and risk factors of intra-abdominal hypertension in children after liver transplantation
10.3761/j.issn.0254-1769.2024.12.011
- VernacularTitle:肝移植术后患儿腹内高压的发生现状及危险因素分析
- Author:
Fangyan LU
1
;
Yanhong DAI
;
Zhiru LI
;
Li JI
;
Yan WANG
;
Huafen WANG
Author Information
1. 310003 杭州市 浙江大学医学院附属第一医院护理部
- Keywords:
Organ Transplantation;
Intra-Abdominal Hypertension;
Risk Factors;
Pediatric Nursing
- From:
Chinese Journal of Nursing
2024;59(12):1484-1489
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the status of intra-abdominal hypertension(IAH)in children after liver transplantation,and to analyze the risk factors,to provide references for clinical medical staff to identify high-risk early,and formulate the prevention and intervention program of IAH after liver transplantation.Methods A prospective cohort study was conducted,and the clinical data of 208 children who received liver transplantation from October 2021 to June 2023 in a tertiary hospital in Zhejiang Province were enrolled.The status of IAH after liver transplantation was described,and participants were divided into 2 groups according to transbladder monitoring intra-abdominal pressure levels.Children with ≥10 mmHg(1 mmHg=0.133 kPa)was classified as an intra-abdominal hypertension group,while those with＜10 mmHg was classified as a non-intra-abdominal hypertension group.Results There were 51 cases(24.52％)which had IAH,including 12 cases(23.53％)of grade I to Ⅱ and 39 cases(76.47％)of grade Ⅲ to Ⅳ in 208 intra-abdominal hypertension in children after liver transplantation.Binary Logistic regression analysis showed that the graft to recipient weight ratio(OR=1.391),duration of postoperative mechanical ventilation(OR=1.006),and postoperative central venous pressure(OR=1.375)were independent risk factors for IAH(P＜0.05).Conclusion The incidence of IAH in children after liver transplantation were high.Greater graft to recipient weight ratio,longer mechanical ventilation time,higher central venous pressure could increase the risk of IAH.During clinical practice,more emphasis should be strengthened on the abdominal pressure dynamic monitoring and providing timely intervention to reduce the occurrence of IAH,and improving the prognosis of children after liver transplantation.
