Research progress on the application of shape memory materials in orthopedics
10.3760/cma.j.cn121113-20230915-00173
- VernacularTitle:形状记忆材料在骨科的应用研究进展
- Author:
Ying WANG
1
;
Jianxiong MA
;
Haohao BAI
;
Xinlong MA
Author Information
1. 天津市天津医院（天津大学天津医院）骨科研究所，天津市骨科生物力学与医学工程重点实验室，天津 300050
- Keywords:
Materials Science;
Orthopedics;
Review
- From:
Chinese Journal of Orthopaedics
2024;44(15):1048-1055
- CountryChina
- Language:Chinese
-
Abstract:
Shape memory materials are intelligent materials that have the effect of remembering and recovering their original shape in response to external stimuli. The preparation methods include heat treatment and laser sintering for alloy-based memory materials, and thermoplastic methods for polymer-based and composite shape memory materials. Shape memory materials have shown great application value in the field of orthopaedics, such as fracture treatment, bone tissue engineering repair, spinal correction and joint replacement. Shape memory materials have excellent biomechanical properties, providing sustained and effective compression, support and torsion resistance during fracture treatment, as well as the advantage of reducing stress masking in internal fixation of fractures. The sustained stress exerted on the surrounding bone tissue due to environmental changes provides continuous corrective force for spinal deformity correction, and improves the durability of prostheses in arthroplasty. Shape memory materials exhibit good biocompatibility and the performance of inducing cell proliferation, making them suitable for fabricating self-adapting" scaffolds for tissue engineering. When precisely filling bone defect sites, they apply mechanical forces to the autogenous bone, stimulate the proliferation and differentiation of osteoblasts, guide bone regeneration and accelerate bone repair. Moreover, shape memory materials can be used as carriers for drug delivery and release, controlling drug release by adjusting temperature, stress and environmental factors to achieve targeted therapy. With the development of 4D printing technology, shape memory materials have extensive potential in the fields of personalized orthopaedic diagnosis and treatment as well as individualized medical device customization.
